TCPOBOP is a constitutive androstane receptor (CAR) agonist. TCPOBOP alleviates Fas-induced liver injury in mice by altering Bcl-2 protein.

 

Brand: BCM

 

Target: BCL

 

Signaling Pathways: Apoptosis

 

In Vivo: TCPOBOP (p.o.; 3 mg/kg; 1-5 days) obviously enhances Liver weight to body weight in LW/BW ratio at 48 hours.

 

Boiling Point: 444.8±45.0 °C(Predicted)

 

pKa: -0.52±0.10(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; Insoluble in Ethanol.

 

Isomeric SMILES: C1=CC(=CC=C1OC2=C(C=C(C=N2)Cl)Cl)OC3=C(C=C(C=N3)Cl)Cl

 

InChIKey: BAFKRPOFIYPKBQ-UHFFFAOYSA-N

 

InChI: InChI=1S/C16H8Cl4N2O2/c17-9-5-13(19)15(21-7-9)23-11-1-2-12(4-3-11)24-16-14(20)6-10(18)8-22-16/h1-8H

 

Attribute
[Chem Name]	3,5-dichloro-2-[4-(3,5-dichloropyridin-2-yl)oxyphenoxy]pyridine
[Synonym]	TCPOBOP
[CAS No.]	76150-91-9
[MDL No.]	MFCD00057368
[Formula]	C16H8Cl4N2O2
[Molecular]	402.06
[Form]	White solid
[Storage]	Sealed in dry, 2-8°C

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