LDN-192960 (Compd 1) is a potent inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50 values of 10 nM and 48 nM, respectively.

 

Brand: BCM

 

Target: DYRK; Haspin Kinase

 

Signaling Pathways: Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors

 

Boiling Point: 536.1±40.0 °C(Predicted)

 

pKa: 9.33±0.10(Predicted)

 

Solubility: Soluble in Water. Insoluble DMSO; Insoluble in Ethanol.

 

GHS: GHS07

 

Isomeric SMILES: COC1=CC2=C(C=C1)N=C3C=CC(=CC3=C2SCCCN)OC  

 

InChIKey: ZFOMCSNUEHMROO-UHFFFAOYSA-N  

 

InChI: InChI=1S/C18H20N2O2S/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16/h4-7,10-11H,3,8-9,19H2,1-2H3

 

Attribute
[Chem Name]	3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine
[Synonym]	LDN-192960
[CAS No.]	184582-62-5
[MDL No.]	MFCD02752814
[Formula]	C18H20N2O2S
[Molecular]	328.43
[Form]	White to light brown powder
[Storage]	2-8°C

Goods Tag