NDI-091143 is a human ATP-citrate lyase (ACLY) inhibitor with a Ki of 7.0 nM and an IC50 of 2.1 nM (ADP-Glo assay).

 

Brand: BCM

 

Target: ATP Citrate Lyase

 

Signaling Pathways: Metabolism

 

Solubility: Soluble in DMSO; Soluble in Ethanol. Insoluble in Water.

 

GHS: GHS07

 

Isomeric SMILES: COC(=O)C1=CC(=C(C(=C1)Cl)O)S(=O)(=O)NC2=C(C=C(C(=C2)C3=CC=CC=C3)F)F  

 

InChIKey: YSTSHUWHIDBZAK-UHFFFAOYSA-N  

 

InChI: InChI=1S/C20H14ClF2NO5S/c1-29-20(26)12-7-14(21)19(25)18(8-12)30(27,28)24-17-9-13(15(22)10-16(17)23)11-5-3-2-4-6-11/h2-10,24-25H,1H3

 

Attribute
[Chem Name]	methyl 3-chloro-5-[(2,4-difluoro-5-phenylphenyl)sulfamoyl]-4-hydroxybenzoate
[Synonym]	NDI-091143; NDI091143; NDI 091143
[CAS No.]	2375840-87-0
[MDL No.]	MFCD32644582
[Formula]	C20H14ClF2NO5S
[Molecular]	453.84
[Form]	A solid
[Storage]	Keep in dark place. Inert atmosphere. Room temperature

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