Voxtalisib (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, and has the strongest effect on p110γ, with IC50 of 9 nM. DNA-PK and mTOR are also inhibited. Phase 1/2.

 

Brand: BCM

 

Boiling Point: 605.0±65.0 °C(Predicted)

 

pKa: 12.54±0.10(Predicted)

 

Solubility: DMSO : 10 mg/mL (37.00 mM; Need ultrasonic)

 

Attribute
[Chem Name]	XL765
[CAS No.]	934493-76-2
[Formula]	C13H14N6O
[Molecular]	270.29000
[Synonym]	SAR245409; Voxtalisib
[Storage]	-20°C
[MDL No.]	MFCD20276656
[Form]	Powder

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