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Nlrp3-in-10 is an effective NLRP3 inhibitor, which inhibits IL-1β release with IC50 of 251.1 nM. Nlrp3-in-10 inhibits NLRP3 inflammasome activation by inhibiting ASC spot formation
Brand: BCM
Targets: NLRP3:251.1 nM (IC50)
InChi Key: ZXMIFRJYIRYWTC-VMPITWQZSA-N
Attribute [Chem Name] (E)-3-(4-bromo-2,5-dimethoxyphenyl)-1-(4-fluorophenyl)prop-2-en-1-one [Synonym] NLRP3-IN-10; ZVN26391; ZVN-26391; ZVN 26391 [CAS No.] 2641826-39-1 [Formula] C17H14BrFO3 [Molecular] 364.011
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