Olitigaltin (TD-139, GM0-139) is a potent and selective galectin-3 inhibitor with Kd values of 0.036 µM, compared with 2.2 µM and 32 µM relative to galectin-1 and galectin-7, respectively. TD-139 can be used in the treatment of idiopathic pulmonary fibrosis (IPF).

 

Brand: BCM

 

Boiling Point: 1017.2±75.0 °C(Predicted)

 

Signaling Pathways: Immunology/Inflammation

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: C1=CC(=CC(=C1)F)C2=CN(N=N2)[C@H]3[C@H]([C@H](O[C@H]([C@@H]3O)S[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)N5C=C(N=N5)C6=CC(=CC=C6)F)O)CO)O  

 

InChIKey: YGIDGBAHDZEYMT-MQFIMZJJSA-N  

 

InChI: InChI=1S/C28H30F2N6O8S/c29-15-5-1-3-13(7-15)17-9-35(33-31-17)21-23(39)19(11-37)43-27(25(21)41)45-28-26(42)22(24(40)20(12-38)44-28)36-10-18(32-34-36)14-4-2-6-16(30)8-14/h1-10,19-28,37-42H,11-12H2/t19-,20-,21+,22+,23+,24+,25-,26-,27+,28+/m1/s1

 

Attribute
[Synonym]	TD139; 33DFTG; Olitigaltin; GB0-139
[CAS No.]	1450824-22-2
[MDL No.]	MFCD29919388
[Formula]	C28H30F2N6O8S
[Molecular]	648.64
[Storage]	Sealed in dry. Store in freezer, under -20°C
[Form]	Off-white solid powder
[Chem Name]	(2R,2'R,3R,3'R,4S,4'S,5R,5'R,6S,6'S)-6,6'-Thiobis(4-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol)

Goods Tag