TDZD-8 (NP 01139) is a non-ATP-competitive inhibitor of GSK-3β with IC50 of 2 μM. It has minimal inhibitory effect on CDK1, casein kinase II, PKA and PKC.

 

Brand: BCM

 

Target: GSK-3

 

Signaling Pathways: PI3K/Akt/mTOR signaling; Stem Cells

 

Boiling Point: 335.5±35.0 °C at 760 mmHg

 

Flashing Point: 156.7±25.9 °C

Melting Point: 63-64.4 °C

 

GHS: GHS08 

 

Isomeric SMILES: CN1C(=O)N(C(=O)S1)CC2=CC=CC=C2  

 

InChIKey: JDSJDASOXWCHPN-UHFFFAOYSA-N  

 

InChI: InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3

 

Attribute
[Chem Name]	4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
[Synonym]	TDZD-8; NP 01139
[CAS No.]	327036-89-5
[MDL No.]	MFCD04973552
[Formula]	C10H10N2O2S
[Molecular]	222.26
[Form]	White solid
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

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