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JNK-IN-7
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Name:JNK-IN-7

  • Catalog No.:
  • BCM006774
  • Chem Name:
  • 3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
  • Synonym:
  • JNK-IN-7; JNK inhibitor
  • CAS No.:
  • 1408064-71-0
  • MDL No.:
  • MFCD25976765
  • Formula:
  • C28H27N7O2
  • Molecular:
  • 493.56
  • Form:
  • Solid
  • Storage:
  • Keep in dark place. Sealed in dry. Room Temperature
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SKU Specification Brand Prices Stock Quantity Cart
BCM006774-25MG 25mg, Purity:98% BCM $45 1 Add Cart
BCM006774-50MG 50mg, Purity:98% BCM $70 2 Add Cart
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Jnk-in-7 is a potent JNK inhibitor with IC50 of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively, which can inhibit the phosphorylation of c-Jun, the direct substrate of JNK kinase.

 

Brand: BCM

 

Target: JNK

 

Signaling Pathways: MAPK

 

pKa: 13.34±0.70(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

GHS: GHS07

 

Isomeric SMILES: CN(C)C/C=C/C(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CN=CC=C4  

 

InChIKey: RADRIIWGHYFWPP-WEVVVXLNSA-N  

 

InChI: InChI=1S/C28H27N7O2/c1-35(2)17-5-9-26(36)31-24-8-3-6-20(18-24)27(37)32-22-10-12-23(13-11-22)33-28-30-16-14-25(34-28)21-7-4-15-29-19-21/h3-16,18-19H,17H2,1-2H3,(H,31,36)(H,32,37)(H,30,33,34)/b9-5+

 

Attribute
[Chem Name] 3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
[Synonym] JNK-IN-7; JNK inhibitor
[CAS No.] 1408064-71-0
[MDL No.] MFCD25976765
[Formula] C28H27N7O2
[Molecular] 493.56
[Form] Solid
[Storage] Keep in dark place. Sealed in dry. Room Temperature

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