DTP3 is a selective GADD45β/MKK7 (growth arrest and DNA-damage inducible β/mitogen-activated protein kinase kinase 7) inhibitor and recovery Activation of MKK7/JNK. DTP3 inhibits cancer-selective NF-κB survival pathways.

 

Brand: BCM

 

Target: DNA/RNA Synthesis; JAK; Others

 

Signaling Pathways: Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Stem Cells; Others; Cell Cycle/Checkpoint; JAK/STAT signaling

 

Solubility: Soluble in DMSO; soluble in Water; soluble in Ethanol.

 

Isomeric SMILES: CC(=O)N[C@H](CC1=CC=C(C=C1)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)N  

 

InChIKey: AOUZPXZGMZUQQS-YPAWHYETSA-N  

 

InChI: InChI=1S/C26H35N7O5/c1-16(34)31-22(15-18-9-11-19(35)12-10-18)25(38)32-20(8-5-13-30-26(28)29)24(37)33-21(23(27)36)14-17-6-3-2-4-7-17/h2-4,6-7,9-12,20-22,35H,5,8,13-15H2,1H3,(H2,27,36)(H,31,34)(H,32,38)(H,33,37)(H4,28,29,30)/t20-,21-,22-/m1/s1 

 

Attribute
[Chem Name]	(2R)-2-[[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
[Synonym]	DTP3; DTP-3
[CAS No.]	1809784-29-9
[MDL No.]	MFCD28348368
[Formula]	C26H35N7O5
[Molecular]	525.6
[Storage]	Keep in dark place. Inert atmosphere. Store in freezer, under -20°C

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