SD-208 is a selective TGF-βRI (ALK5) inhibitor with an IC50 of 48 nM, which is more than 100 times more selective than TGF-βRII.

 

Brand: BCM

 

Target: TGF-beta/Smad

 

Solubility: Soluble in DMSO (warmed with 50ºC water bath). Insoluble in Water; insoluble in Ethanol.

 

GHS: GHS07

 

Isomeric SMILES: C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F  

 

InChIKey: BERLXWPRSBJFHO-UHFFFAOYSA-N  

 

InChI: InChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25) 

 

Attribute
[Chem Name]	2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine
[Synonym]	SD-208
[CAS No.]	627536-09-8
[MDL No.]	MFCD09038685
[Formula]	C17H10ClFN6
[Molecular]	352.75
[Form]	Off-white to tan powder
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

Goods Tag