SX-682 is an orally active small-molecule allosteric inhibitor of CXCR1 and CXCR2 that blocks tumor MDSC recruitment and enhances T cell activation and anti-tumor immunity.

 

Brand: BCM

 

Target: CXCR

 

Signaling Pathways: Autophagy; GPCR/G Protein; Immunology/Inflammation

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

pKa: 8.18±0.53(Predicted)

 

GHS: GHS07

 

Isomeric SMILES: B(C1=C(C=C(C=C1)OC(F)(F)F)CSC2=NC=C(C=N2)C(=O)NC3=CC=C(C=C3)F)(O)O  

 

InChIKey: SDUDZBCEHIZMFZ-UHFFFAOYSA-N  

 

InChI: InChI=1S/C19H14BF4N3O4S/c21-13-1-3-14(4-2-13)27-17(28)12-8-25-18(26-9-12)32-10-11-7-15(31-19(22,23)24)5-6-16(11)20(29)30/h1-9,29-30H,10H2,(H,27,28) 

 

Attribute
[Chem Name]	[2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid
[Synonym]	SX-682
[CAS No.]	1648843-04-2
[EINECS]	604-604-1
[MDL No.]	MFCD28502254
[Formula]	C19H14BF4N3O4S
[Molecular]	467.2
[Form]	Off-white solid
[Risk Codes]	H302-H315-H319-H335
[Storage]	Inert atmosphere, 2-8°C

Goods Tag