LC3-mHTT-IN-AN1 is an MHTT-LC3 linker compound that interacts with mutant Huntington protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 reduces mHTT levels in cultured Huntington's disease (HD) mouse neurons in an allele-selective manner.

 

Brand: BCM

 

In Vitro: LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured HD mouse neurons.

 

Boiling Point: 586.1±50.0 °C at 760 mmHg

 

Flashing Point: 308.3±30.1 °C

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

Isomeric SMILES: C1=CC2=C(C=C1Br)/C(=C/C3=CC(=C(C(=C3)Br)O)O)/C(=O)N2  

 

InChIKey: GPKLWRHHVIBYEO-KMKOMSMNSA-N  

 

InChI: InChI=1S/C15H9Br2NO3/c16-8-1-2-12-9(6-8)10(15(21)18-12)3-7-4-11(17)14(20)13(19)5-7/h1-6,19-20H,(H,18,21)/b10-3-

 

Attribute
[Chem Name]	(3Z)-5-bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-1H-indol-2-one
[Synonym]	LC3-mHTT-IN-AN1
[CAS No.]	486443-73-6
[MDL No.]	MFCD03235520
[Formula]	C15H9Br2NO3
[Molecular]	411.04
[Form]	Solid powder
[Storage]	Sealed in dry, 2-8°C

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