BMS-345541 is a highly selective inhibitor of the catalytic subunit, acting on IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively, in cell-free tests.

 

Brand: BCM

 

Target: IκB/IKK

 

Signaling Pathways: NF-κB

 

Boiling Point: 449.5±45.0 °C at 760 mmHg

 

Flash Point: 225.6±28.7 °C

 

Vapour Pressure: 0.0±1.1 mmHg at 25°C

 

pKa: 9.02±0.10(Predicted)

 

Solubility: Soluble in DMSO. Insoluble in Water; insoluble in Ethanol.

 

GHS: GHS07

 

Isomeric SMILES: CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN  

 

InChIKey: PSPFQEBFYXJZEV-UHFFFAOYSA-N  

 

InChI: InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)

 

Attribute
[Chem Name]	N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
[Synonym]	BMS-345541; IKK Inhibitor III
[CAS No.]	445430-58-0
[MDL No.]	MFCD18089812
[Formula]	C14H17N5
[Molecular]	255.32
[Form]	Solid Powder
[Storage]	Keep in dark place. Inert atmosphere, 2-8°C

Goods Tag