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BTZO-1 can be combined with macrophage migration inhibitory factor (MIF), whose Kd value is 68.6 nM. BTZO-1 starvation activates antioxidant response element (ARE) -mediated gene expression and inhibits oxidative stress-induced cardiomyocyte apoptosis in vitro.
Brand: BCM
Target: Apoptosis
Signaling Pathways: Apoptosis
Boiling Point: 454.9±37.0 °C(Predicted)
pKa: -0.01±0.19(Predicted)
Solubility: Soluble in DMSO; soluble in Ethanol. Insolube in Water.
GHS: GHS07
Isomeric SMILES: C1=CC=C2C(=C1)C(=O)N=C(S2)C3=CC=CC=N3
InChIKey: GBAKVEWPYUIGHN-UHFFFAOYSA-N
InChI: InChI=1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H
Attribute [Chem Name] 2-pyridin-2-yl-1,3-benzothiazin-4-one [Synonym] BTZO-1 [CAS No.] 99420-15-2 [MDL No.] MFCD19690951 [Formula] C13H8N2OS [Molecular] 240.28 [Form] White to tan powder [Storage] Sealed in dry, 2-8°C
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