Wdr5-0103 (WD-Repeat Protein 5-0103) is a small molecule antagonist of WDR5 (WD40 repeat protein 5) with a Kd value of 450 nM.

 

Brand: BCM

 

Target: JAK; Histone Methyltransferase

 

Signaling Pathways: Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells

 

Boiling Point: 495.2±45.0 °C(Predicted)

 

pKa: 12.96±0.70(Predicted)

 

Solubility: Soluble in DMSO; soluble in Ethanol. Insoluble in Water.

 

GHS: GHS09

 

Isomeric SMILES: CN1CCN(CC1)C2=C(C=C(C=C2)C(=O)OC)NC(=O)C3=CC(=CC=C3)OC  

 

InChIKey: ZPLBXOVTSNRBFB-UHFFFAOYSA-N  

 

InChI: InChI=1S/C21H25N3O4/c1-23-9-11-24(12-10-23)19-8-7-16(21(26)28-3)14-18(19)22-20(25)15-5-4-6-17(13-15)27-2/h4-8,13-14H,9-12H2,1-3H3,(H,22,25) 

 

Attribute
[Chem Name]	methyl 3-[(3-methoxybenzoyl)amino]-4-(4-methylpiperazin-1-yl)benzoate
[Synonym]	WDR5-0103; WD-Repeat Protein 5-0103
[CAS No.]	890190-22-4
[MDL No.]	MFCD07086826
[Formula]	C21H25N3O4
[Molecular]	383.44
[Form]	White to beige powder
[Storage]	Sealed in dry, 2-8°C

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